Which glands secretes hormones directly into the bloodstream?

14.1: Structures of the Endocrine System

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This diagram shows the endocrine glands and cells that are located throughout the body. The endocrine system organs include the pineal gland and pituitary gland in the brain. The pituitary is located on the anterior side of the thalamus while the pineal gland is located on the posterior side of the thalamus. The thyroid gland is a butterfly-shaped gland that wraps around the trachea within the neck. Four small, disc-shaped parathyroid glands are embedded into the posterior side of the thyroid. The adrenal glands are located on top of the kidneys. The pancreas is located at the center of the abdomen. In females, the two ovaries are connected to the uterus by two long, curved, tubes in the pelvic region. In males, the two testes are located in the scrotum below the penis.

The endocrine system consists of cells, tissues, and organs that secrete hormones as a primary or secondary function. The endocrine gland is the major player in this system. The primary function of these ductless glands is to secrete their hormones directly into the surrounding fluid. The interstitial fluid and the blood vessels then transport the hormones throughout the body. The endocrine system includes the pituitary, thyroid, parathyroid, adrenal, and pineal glands (Figure \(\PageIndex\)). Some of these glands have both endocrine and non-endocrine functions. For example, the pancreas contains cells that function in digestion as well as cells that secrete the hormones insulin and glucagon, which regulate blood glucose levels. The hypothalamus, thymus, heart, kidneys, stomach, small intestine, liver, skin, female ovaries, and male testes are other organs that contain cells with endocrine function. Moreover, adipose tissue has long been known to produce hormones, and recent research has revealed that even bone tissue has endocrine functions. The ductless endocrine glands are not to be confused with the body’s exocrine system, whose glands release their secretions through ducts. Examples of exocrine glands include the sebaceous and sweat glands of the skin. As just noted, the pancreas also has an exocrine function: most of its cells secrete pancreatic juice through the pancreatic and accessory ducts to the lumen of the small intestine

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