Biology of sweat glands and their disorders. I. Normal sweat gland function
The basic mechanisms of sweat gland function and an updated review of some relatively common disorders of sweat secretion, are presented. Although sweat secretion and ductal absorption are basically biophysical and biologic cellular processes, a detailed description of the basic biophysical principles of membrane transport has been avoided to make the discussion more readable. The cited references will, however, help those readers primarily interested in the basic details of sweat gland function. Part I of this article includes a discussion of morphologic characteristics, central and peripheral nervous control of sweat secretion, neurotransmitters, intracellular mediators and stimulus secretion coupling, Na-K-Cl cotransport model for the ionic mechanism of sweat secretion, ingredients of sweat, ductal function, the pathogenesis of abnormal sweat gland function in cystic fibrosis, and the discovery of the apoeccrine sweat gland. Part II, to be published in the May issue of the Journal, reviews reports of all those major disorders of hyperhidrosis and hypohidrosis that have appeared in the literature during the past 10 years. It is hoped that this review will serve as a resource for clinicians who encounter puzzling disorders of sweating in their patients, as well as for investigators who wish to obtain a quick update on sweat gland function.
Similar articles
Quinton PM. Quinton PM. Annu Rev Med. 1983;34:429-52. doi: 10.1146/annurev.me.34.020183.002241. Annu Rev Med. 1983. PMID: 6344770 Review.
Sato K, Sato F. Sato K, et al. Am J Physiol. 1987 Jan;252(1 Pt 2):R181-7. doi: 10.1152/ajpregu.1987.252.1.R181. Am J Physiol. 1987. PMID: 3544873
Murota H. Murota H. Curr Probl Dermatol. 2016;51:57-61. doi: 10.1159/000446760. Epub 2016 Aug 30. Curr Probl Dermatol. 2016. PMID: 27584963 Review.
Sato K, Sato F. Sato K, et al. J Lab Clin Med. 1990 Apr;115(4):504-11. J Lab Clin Med. 1990. PMID: 2182749
Sato K, Kang WH, Saga K, Sato KT. Sato K, et al. J Am Acad Dermatol. 1989 May;20(5 Pt 1):713-26. doi: 10.1016/s0190-9622(89)70081-5. J Am Acad Dermatol. 1989. PMID: 2654213 Review.
Cited by
Murayama N, Miyaki T, Okuzaki D, Shibata Y, Koji T, Inoue A, Aoki J, Hayashi H, Tanaka Y, Murota H. Murayama N, et al. JID Innov. 2023 Mar 15;3(4):100196. doi: 10.1016/j.xjidi.2023.100196. eCollection 2023 Jul. JID Innov. 2023. PMID: 37533582 Free PMC article.
Shitanda I, Muramatsu N, Kimura R, Takahashi N, Watanabe K, Matsui H, Loew N, Motosuke M, Mukaimoto T, Kobayashi M, Mitsuhara T, Sugita Y, Matsuo K, Yanagita S, Suzuki T, Watanabe H, Itagaki M. Shitanda I, et al. ACS Sens. 2023 Jul 28;8(7):2889-2895. doi: 10.1021/acssensors.3c01027. Epub 2023 Jun 15. ACS Sens. 2023. PMID: 37318827 Free PMC article.
Li J, Ding Q, Wang H, Wu Z, Gui X, Li C, Hu N, Tao K, Wu J. Li J, et al. Nanomicro Lett. 2023 Apr 15;15(1):105. doi: 10.1007/s40820-023-01079-5. Nanomicro Lett. 2023. PMID: 37060483 Free PMC article. Review.
Yuan X, Li C, Yin X, Yang Y, Ji B, Niu Y, Ren L. Yuan X, et al. Biosensors (Basel). 2023 Feb 23;13(3):313. doi: 10.3390/bios13030313. Biosensors (Basel). 2023. PMID: 36979525 Free PMC article. Review.
Min J, Tu J, Xu C, Lukas H, Shin S, Yang Y, Solomon SA, Mukasa D, Gao W. Min J, et al. Chem Rev. 2023 Apr 26;123(8):5049-5138. doi: 10.1021/acs.chemrev.2c00823. Epub 2023 Mar 27. Chem Rev. 2023. PMID: 36971504 Review.